Rome, the Eternal City, is a treasure trove of history, art, and culture. If you have just 48 hours, careful planning is essential to make the most of your trip. This guide will take you through the must see places in Rome, where to buy tickets efficiently, and the best dining spots.
Day 1: Ancient Rome & The Vatican City
Morning: The Colosseum & Roman Forum
Kick off your Roman adventure bright and early with the city’s most iconic landmark:
- Colosseum – Step inside this legendary amphitheater and imagine the roar of the crowd as gladiators battled for glory.
- Ticket Tip: Buy a combined ticket for the Colosseum, Roman Forum, and Palatine Hill online to save time and money.
2. Roman Forum – Wander through the political and social heart of Ancient Rome, a site often featured in the best Rome tours for its rich history and iconic ruins.
3. Palatine Hill – Enjoy stunning panoramic views from the legendary birthplace of Rome’s emperors.
Bonus Experience: Try an immersive audio guide from WorldMuseum to bring the ruins of Ancient Rome to life: Ancient Rome walk.
Lunch: Pasta and More
- Top Pick: For a fine dining experience with a stunning Colosseum view, head to Ristorante Aroma (Via Labicana, 125).
- Casual Option: If you prefer something relaxed, try Ristorante Angelino ai Fori (Largo Corrado Ricci, 40), famous for traditional Roman dishes like amatriciana and cacio e pepe.
Afternoon: Vatican City – Art & Spirituality

4. Vatican Museums & Sistine Chapel – Behold the breathtaking masterpieces of Michelangelo and Raphael in one of the true highlights of Rome, where art, history, and spirituality come together in unforgettable harmony.
- Ticket Tip: Get skip-the-line tickets in advance at museivaticani.va.
- St. Peter’s Basilica – Enter the world’s largest church and admire Michelangelo’s Pietà and Bernini’s Baldachin.
- Best View: Climb to the dome for breathtaking city views.
Dinner: Authentic Roman Cuisine
- Recommended Spot: Osteria da Fortunata (Via del Pellegrino, 11) – Famous for handmade pasta and a cozy Roman atmosphere.
- Want dinner with a view? Check out our list of the most beautiful terrace restaurants and bars in Rome

Day 2: Baroque Beauty & Hidden Gems
Morning: Piazza & Fountains

6. Piazza Navona – One of the most beautiful squares in the city, featuring Bernini’s Fountain of the Four Rivers, and undoubtedly one of the must go places in Rome for art, atmosphere, and people-watching.
Gelato Break!
- Top Pick: Gelateria della Palma (Via della Maddalena, 19) – Over 150 flavors to choose from!
- Classic Choice: Giolitti (Via degli Uffici del Vicario, 40) – One of Rome’s oldest gelaterias, known for its rich, creamy textures.
- More sweet spots? Check out our guide to The best gelato in Rome!
- Pantheon – Step inside the best-preserved ancient Roman temple.
- Ticket Tip: Entry is now ticketed (available at pantheonroma.com).
- Trevi Fountain – Toss a coin over your left shoulder to ensure your return to Rome.
Bonus Experience: WorldMuseum’s Varoque Rome interactive audio tour will guide you through these and other stunning baroque gems, making it a perfect way to explore some of the most iconic places to visit in Rome in just about 3 hours.
Lunch: Casual Yet Delicious
- Recommended Spot: Pane e Salame (Via di Santa Maria in Via, 19) – A great place for sandwiches and Italian cured meats.
Afternoon: Spanish Steps & Trastevere
- Spanish Steps & Piazza di Spagna – Relax at this famous staircase before heading towards the final neighborhood.
- Trastevere – Wander through this charming district, known for its cobblestone streets and authentic Roman vibes. With gems like the Basilica di Santa Maria in Trastevere, it’s easily one of the must see places in Rome Italy for those seeking local charm and timeless atmosphere.

Dinner: A True Roman Dining Experience
- Recommended Spot: Tonnarello (Via della Paglia, 1) – A must-visit for classic Roman dishes like cacio e pepe and carbonara.
Final Tips for an Efficient Visit
- Transport: Use the metro (Line A & B) and buses for quick movement between locations.
- City Passes: Consider the Roma Pass or Omnia Vatican & Rome Card for free entry and transport benefits.
- Early Start: Arrive at attractions early to beat the crowds.
Whether you’re a history buff, a foodie, or a casual traveler, this 48-hour itinerary offers the perfect mix of culture, cuisine, and unforgettable sights. With smart planning and a spirit of adventure, you’ll experience many of the must see places in Rome and capture the essence of the Eternal City in just two days. And remember—no matter how much you manage to see, Rome always welcomes you back for more.